British Air Force Typhoon fighter aircraft have joined forces with French warplanes in a combined operation against an underground arms cache in Syrian territory used by the IS group, according to the British defence ministry.
The location, located using intelligence, was thought to be containing munitions and bombs, the statement said, and was situated in hills just north of the ancient city of Palmyra in Syria's central region.
"Our aircraft utilized Paveway IV guided bombs to strike a number of access tunnels leading to the depot... initial indications suggest the objective was successfully hit," the MoD said.
There was no indication of any civilian casualties in the strike late on Saturday and all the aircraft returned to base without incident, the MoD added.
The Typhoon FGR4s were backed up by a Voyager refuelling tanker.
IS - also known as Daesh - enforced militant control over parts of Syria and Iraq prior to its 2019 collapse.
"This strike shows the UK's leading role, and commitment to operate in unison with allied nations, to stamp out any re-emergence of the terrorist group and their dangerous and violent ideologies in the region," UK Defence Secretary John Healey said.
British military aircraft have performed surveillance missions over Syrian airspace to "deter any attempted resurgence" of IS following its defeat at the battle of Baghuz in 2019, the MoD reported.
"I must thank all the members of the UK armed forces involved in this operation for their professionalism and their valour," he commented. "They were among a great many British troops deployed over the holidays. This mission, to take out dangerous terrorists who endanger our safety, shows how our armed forces are prepared to act, continuously, keeping Britain secure at home and influential overseas."
In December, the United States armed forces conducted what it described as a "massive strike" targeting Daesh sites in Syria, after an ambush killed two US servicemembers and a civilian linguist in Palmyra.
The United Nations estimates Daesh still maintains roughly 5-7 thousand combatants in both countries.
